Recombinant Prostate Specific Antigen 抗体 (AA 150-250)
Quick Overview for Recombinant Prostate Specific Antigen 抗体 (AA 150-250) (ABIN7126557)
抗原
See all Prostate Specific Antigen (PSA) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 150-250
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特异性
- Prostate-specific antigen (PSA) is a single-chain glycoprotein of 237 amino acids containing approximately 8 % carbohydrate. It is a serine protease produced almost exclusively by prostatic epithelial cells. Immunohistochemically PSA is expressed in the highly specialized apically-superficial layer of female and male secretory cells of the prostate gland, and is readily demonstrated in adenocarcinomas of the prostate in about 99 % of the cases. There is a correlation between malignancy grade and intensity of staining, high grade carcinomas displaying weaker expression. About 1 % of poorly differentiated carcinomas have been negative for PSA. Due to the high specificity of PSA for prostatic glandular epithelium, it is very useful in identifying prostatic carcinoma in the prostate and in the adjacent organs often affected by epithelial malignancies, i.e. rectum and urinary bladder. PSA may be used in a panel together with NKX3.1 and Prostein, which are at least as sensitive and slightly more specific than PSA.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Synthetic peptide corresponding to PSA residues within aa150-250 of PSA was used as an immunogen.
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亚型
- IgG
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anti-Prostate Specific Antigen (PSA) (AA 1-100) antibody
PSA 适用: 人 IHC, WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Prostate Specific Antigen (PSA) (AA 26-251) antibodyPSA 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5A11E2 unconjugated
anti-Prostate Specific Antigen (PSA) antibodyPSA 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal A67-B-E3 unconjugated
anti-Prostate Specific Antigen (PSA) (AA 39-261) antibodyPSA 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Prostate Specific Antigen (PSA) antibodyPSA 适用: 人 IHC, WB, IHC (p), FACS, ICC, IHC (fro), ELISpot 宿主: 小鼠 Monoclonal C3F12 unconjugated
anti-Prostate Specific Antigen (PSA) antibodyPSA 适用: 人 IHC, StM, ISt 宿主: 兔 Monoclonal KLK3-2871R unconjugated Recombinant Antibody
anti-Prostate Specific Antigen (PSA) (AA 150-250) antibodyPSA 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-603R unconjugated Recombinant Antibody
anti-Prostate Specific Antigen (PSA) antibodyPSA 适用: 人, 兔 ELISA, WB, IHC (p), IF (p) 宿主: 小鼠 Monoclonal Pa3 unconjugated
anti-Prostate Specific Antigen (PSA) antibodyPSA 适用: 人 WB, IHC (p), IF (p) 宿主: 小鼠 Monoclonal PA5 unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: PC12 cells. Normal prostate or prostate carcinoma tissues.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Prostate Specific Antigen (PSA)
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别名
- KLK3
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背景
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Antigen, prostate-specific (APS), Gamma-seminoprotein, hK3, Kallikrein related peptidase 3, Kallikrein-3 (KLK3), KLK2A1, P-30 antigen, Semenogelase, Seminin,Prostate Specific Antigen (PSA)
Cellular localisation: Secreted -
分子量
- 29kDa
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基因ID
- 354, 171995
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UniProt
- P07288
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途径
- Complement System
抗原
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