IGFBP3 抗体
Quick Overview for IGFBP3 抗体 (ABIN7126549)
抗原
See all IGFBP3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The Insulin-like growth factor-binding proteins, or IGFBPs, are a family of homologous proteins that have co-evolved with the IGFs. They serve not only as shuttle molecules for the soluble IGFs, but also confer a level of regulation to the IGF signaling system. Physical association of the IGFBPs with IGF influences the bio-availability of the growth factors, as well as their concentration and distribution in the extracellular environment. In addition, the IGFBPs appear to have biological activity independent of the IGFs. Seven IGFBPs have thus far been described, each differing in their tissue distribution, half-lives and modulation of IGF interactions with their receptors. IGFBP3 is the most abundant IGFBP and is complexed with roughly 80 % of the serum IGFs. Both IGFBP3 and IGFBP4 are released by dermal fibroblasts in response to incision injury.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human full-length IGFBP3 protein
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亚型
- IgG2b
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anti-Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 186-292) antibody
IGFBP3 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 182-291) antibodyIGFBP3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G6 unconjugated
anti-Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 162-189) antibodyIGFBP3 适用: 人, 小鼠, Hamster WB 宿主: 兔 Polyclonal RB28430 unconjugated
anti-Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 152-292) antibodyIGFBP3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 135-277) antibodyIGFBP3 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D14 unconjugated
anti-Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 137-274) antibodyIGFBP3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 106-241) antibodyIGFBP3 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (Ser53) antibodyIGFBP3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 1-291) antibodyIGFBP3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 3 (IGFBP3) (AA 100-200) antibodyIGFBP3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: U-87 or A-431 cells.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))
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别名
- IGFBP3
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背景
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Acid stable subunit of the 140 K IGF complex, Binding protein 29, Binding protein 53, BP53, Growth hormone dependent binding protein, IBP3, IGF binding protein 3, IGFBP3, Insulin-like growth factor binding protein 3 precursor,IGFBP3
Cellular localisation: Secreted. Localized to vesicles, cytosol and nucleoplasm. -
分子量
- 40/44kDa
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基因ID
- 3486, 450230, 697535
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途径
- Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Growth Factor Binding
抗原
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