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VPS26B 抗体

This anti-VPS26B antibody is a 兔 多克隆 antibody detecting VPS26B in ELISA 和 WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7120705
发货至: 中国

Quick Overview for VPS26B 抗体 (ABIN7120705)

抗原

See all VPS26B 抗体
VPS26B (Vacuolar Protein Sorting 26 Homolog B (VPS26B))

适用

  • 20
  • 14
  • 9
  • 2
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  • 2
  • 1
  • 1
  • 1
  • 1
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人, 小鼠, 大鼠

宿主

  • 20

克隆类型

  • 20
多克隆

标记

  • 10
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This VPS26B antibody is un-conjugated

应用范围

  • 11
  • 10
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  • 3
  • 1
  • 1
ELISA, Western Blotting (WB)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    vacuolar protein sorting 26 homolog B(S. pombe)

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:5000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    VPS26B (Vacuolar Protein Sorting 26 Homolog B (VPS26B))

    别名

    VPS26B

    背景

    Synonyms:Pep8b, Vesicle protein sorting 26B, VPS26B Background:Acts as component of the retromer cargo-selective complex(CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network(TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde transport of WLS distinct from the SNX-BAR retromer pathway. The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins. The CSC seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5. May be involved in retrograde transport of SORT1 but not of IGF2R. Acts redundantly with VSP26A in SNX-27 mediated endocytic recycling of SLC2A1/GLUT1(By similarity).

    分子量

    39 kDa

    基因ID

    112936

    UniProt

    Q4G0F5

    途径

    Cellular Glucan Metabolic Process
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