VPS11 抗体
Quick Overview for VPS11 抗体 (ABIN7120703)
抗原
See all VPS11 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- vacuolar protein sorting 11 homolog(S. cerevisiae)
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亚型
- IgG
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anti-Vacuolar Protein Sorting 11 Homolog (VPS11) antibody
VPS11 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Vacuolar Protein Sorting 11 Homolog (VPS11) (Center) antibodyVPS11 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 11 Homolog (VPS11) (Internal Region) antibodyVerified VPS11 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 11 Homolog (VPS11) (AA 842-941) antibodyVPS11 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H1 unconjugated
anti-Vacuolar Protein Sorting 11 Homolog (VPS11) (Internal Region) antibodyVPS11 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 11 Homolog (VPS11) (AA 692-941) antibodyVPS11 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 11 Homolog (VPS11) (AA 842-941) antibodyVPS11 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:5000, IF: 1:10-1:100, IP: 1:200-1:2000, FC:N/A
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- VPS11 (Vacuolar Protein Sorting 11 Homolog (VPS11))
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别名
- VPS11
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背景
- Synonyms:END1, hVPS11, PEP5, RING finger protein 108, RNF108, VPS11 Background:Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations(PubMed:11382755, PubMed:23351085, PubMed:24554770, PubMed:25266290, PubMed:25783203). Required for fusion of endosomes and autophagosomes with lysosomes(PubMed:25783203). Involved in cargo transport from early to late endosomes and required for the transition from early to late endosomes(PubMed:21148287). Involved in the retrograde Shiga toxin transport(PubMed:23593995).
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分子量
- 108 kDa
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基因ID
- 55823
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UniProt
- Q9H270
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途径
- SARS-CoV-2 Protein Interactome
抗原
-
