Ubiquilin 1 抗体
Quick Overview for Ubiquilin 1 抗体 (ABIN7120456)
抗原
See all Ubiquilin 1 (UBQLN1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- UBQLN1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- ubiquilin 1
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亚型
- IgG
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anti-Ubiquilin 1 (UBQLN1) (AA 290-339) antibody
UBQLN1 适用: 人, Cow, 犬, 豚鼠, 马, 兔, 绵羊, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquilin 1 (UBQLN1) (AA 296-326) antibodyUBQLN1 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquilin 1 (UBQLN1) (AA 1-300) antibodyUBQLN1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquilin 1 (UBQLN1) (AA 1-589) antibodyUBQLN1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C6-A3 unconjugated
anti-Ubiquilin 1 (UBQLN1) (AA 1-589) antibodyUBQLN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C6-B7 unconjugated
anti-Ubiquilin 1 (UBQLN1) (Internal Region) antibodyUBQLN1 适用: 人 WB, ELISA, IHC, IHC (p), IP 宿主: 小鼠 Monoclonal 3D5E2 unconjugated
anti-Ubiquilin 1 (UBQLN1) (AA 296-326) antibodyUBQLN1 适用: 人, 小鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal RB4554 unconjugated
anti-Ubiquilin 1 (UBQLN1) antibodyUBQLN1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquilin 1 (UBQLN1) (AA 19-49), (N-Term) antibodyUBQLN1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB4615 unconjugated
anti-Ubiquilin 1 (UBQLN1) (AA 40-70) antibodyUBQLN1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:200-1:1000, IF: 1:10-1:100, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- Ubiquilin 1 (UBQLN1)
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别名
- UBQLN1
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背景
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Synonyms: Ubiquilin-1|Protein linking IAP with cytoskeleton 1 (PLIC-1, hPLIC-1)|UBQLN1|DA41|PLIC1
Background: UBQLN1, also known as DSK2 or Ubiquilin 1, is an ubiquitin-like proteinis contains a?N-terminal?ubiquitin-like?domain?and a C-terminal ubiquitin-associated domain.?They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation.Ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with?Alzheimer's?and?Parkinson's?disease. Two transcript variants encoding different isoforms have been found for this gene. Higher levels of ubiquilin-1 in the brain decreased malformation of the APP molecule which plays a key role in triggering Alzheimers disease.Conversely, lower levels of ubiquilin-1 in the brain were associated with increased malformation of APP?(PMID: 21852239). This antibody detects 70kD band of UBQLN1.
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分子量
- 71 kDa
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UniProt
- Q9UMX0
抗原
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