p63 抗体 (AA 381-680)
Quick Overview for p63 抗体 (AA 381-680) (ABIN7120423)
抗原
See all p63 (TP63) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 381-680
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原理
- TP63 antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 381-680aa
Immunogen: tumor protein p63
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亚型
- IgG1
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anti-Tumor Protein P63 (TP63) antibody
KO Validated TP63 适用: 人 WB, IF, ICC, IP, IHC (p), IHC (fro), PLA 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) (AA 421-680) antibodyTP63 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) (AA 5-17) antibodyTP63 适用: 人, 小鼠, 大鼠, Cow WB, IHC, StM 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) antibodyTP63 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal TP63-2428 unconjugated
anti-Tumor Protein P63 (TP63) (AA 3-106) antibodyTP63 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal TP63-1786 unconjugated
anti-Tumor Protein P63 (TP63) (AA 664-680), (C-Term) antibodyTP63 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) antibodyTP63 适用: 人, 小鼠 IHC, StM 宿主: 小鼠 Monoclonal TP63-11 unconjugated
anti-Tumor Protein P63 (TP63) (C-Term) antibodyTP63 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) antibodyTP63 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) (pSer455) antibodyTP63 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- p63 (TP63) (Tumor Protein P63 (TP63))
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别名
- TP63
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背景
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Synonyms: Tumor protein 63 (p63)|Chronic ulcerative stomatitis protein (CUSP)|Keratinocyte transcription factor KET|Transformation-related protein 63 (TP63)|Tumor protein p73-like (p73L)|p40|p51|TP63|KET|P63|P73H|P73L|TP73L
Background: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter.
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分子量
- 68 kDa
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基因ID
- 8626
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UniProt
- Q9H3D4
抗原
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