Tubulin 抗体 (acLys40)
This anti-Tubulin antibody is a 小鼠 单克隆 antibody detecting Tubulin in WB, IF, ELISA 和 IHC. Suitable for 人, 小鼠, 犬 和 大鼠.
Quick Overview for Tubulin 抗体 (acLys40) (ABIN7120355)
抗原
See all Tubulin (TUB) 抗体
Tubulin (TUB)
适用
人, 小鼠, 犬, 大鼠
宿主
小鼠
克隆类型
单克隆
标记
This Tubulin antibody is un-conjugated
应用范围
Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (IHC)
克隆位点
6A10
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抗原表位
- acLys40
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- tubulin, alpha 1a
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亚型
- IgG1
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应用备注
- WB: 1:500-1:5000, IF: 1:20-1:200, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- Tubulin (TUB)
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别名
- tubulin
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背景
- Synonyms:Acetylated alpha tubulin, Acetylated tubulin, acetylated-a-tubulin, acetyl-a-tubulin, alpha tubulin, Alpha tubulin 3, tubulin,TUBA1A Background:Tubulin, composed of heterodimers of alpha and beta tubulin, is the mainly component of microtubules which play important roles in cell motility, mitosis, and intracellular vesicle transport. Both alpha and beta tubulin undergo several posttranslational modifications such as polyglutamylation and acetylation/deacetylation. Tubulin acetylation occurs on lysine-40 at the N-terminal of alpha tubulin and is conserved across species. The histone deacetylase HDAC6 and SIRT2 has been identified as tubulin deacetylases. Reversible acetylation of alpha tubulin may be implicated in regulating microtubule stability, cell motility, and axon regeneration. The level of acetylated tubulin has been linked to epithelial malignancies and sensitivity to chemotherapy. In addition, acetylated tubulin has been widely used as a marker for primary cilia. This antibody is specific to the acetylated tubulin, it does not recognize non-acetylated tubulin.
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分子量
- 52 kDa
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基因ID
- 7846
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UniProt
- Q71U36
抗原
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