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TFE3 抗体 (AA 1-300)

This anti-TFE3 antibody is a 兔 多克隆 antibody detecting TFE3 in WB, ELISA, IHC 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7120074
发货至: 中国

Quick Overview for TFE3 抗体 (AA 1-300) (ABIN7120074)

抗原

See all TFE3 抗体
TFE3 (Transcription Factor E3 (TFE3))

适用

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人, 小鼠, 大鼠

宿主

  • 56
  • 2
  • 1
  • 1

克隆类型

  • 57
  • 3
多克隆

标记

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This TFE3 antibody is un-conjugated

应用范围

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  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
  • 抗原表位

    • 9
    • 8
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    • 2
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    • 1
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    • 1
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    AA 1-300

    原理

    TFE3 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 1-300aa

    Immunogen: transcription factor binding to IGHM enhancer 3

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:5000, IP: 1:200-1:2000, IHC: 1:50-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    TFE3 (Transcription Factor E3 (TFE3))

    别名

    TFE3

    背景

    Synonyms: Transcription factor E3|Class E basic helix-loop-helix protein 33 (bHLHe33)|TFE3|BHLHE33

    Background: Transcription factor that specifically recognizes and binds E-box sequences(5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.

    分子量

    65 kDa

    基因ID

    7030

    UniProt

    P19532
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