TXNRD1 抗体
Quick Overview for TXNRD1 抗体 (ABIN7119913)
抗原
See all TXNRD1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TXNRD1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- thioredoxin reductase 1
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亚型
- IgG
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应用备注
- WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:10-1:100, IP: 1:200-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))
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别名
- TXNRD1
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背景
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Synonyms: Thioredoxin reductase 1, cytoplasmic (TR)|Gene associated with retinoic and interferon-induced mortality 12 protein (GRIM-12, Gene associated with retinoic and IFN-induced mortality 12 protein)|KM-102-derived reductase-like factor|Peroxidase TXNRD1|Thioredoxin reductase TR1|TXNRD1|GRIM12|KDRF
Background: Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
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分子量
- 54 kDa
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基因ID
- 7296
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UniProt
- Q16881
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途径
- Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis
抗原
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