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SOCS1 抗体

This anti-SOCS1 antibody is a 兔 多克隆 antibody detecting SOCS1 in WB, ELISA, IHC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7119604
发货至: 中国

Quick Overview for SOCS1 抗体 (ABIN7119604)

抗原

See all SOCS1 抗体
SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))

适用

  • 51
  • 35
  • 30
  • 6
  • 5
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  • 3
  • 3
  • 3
  • 3
  • 2
人, 小鼠, 大鼠

宿主

  • 48
  • 7
  • 2

克隆类型

  • 52
  • 5
多克隆

标记

  • 37
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SOCS1 antibody is un-conjugated

应用范围

  • 41
  • 18
  • 18
  • 12
  • 9
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  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 原理

    SOCS1 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: peptide

    Immunogen: Suppressor of cytokine signaling 1

    亚型

    IgG
  • 应用备注

    WB: 1:500 - 1:2000, IHC: 1:50-1:200, IF: 1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))

    别名

    SOCS1

    背景

    Synonyms: Suppressor of cytokine signaling 1 (SOCS-1)|JAK-binding protein (JAB)|STAT-induced STAT inhibitor 1 (SSI-1)|Tec-interacting protein 3 (TIP-3)|SOCS1|SSI1|TIP3

    Background: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

    分子量

    24 kDa

    基因ID

    8651

    UniProt

    O15524

    途径

    JAK/STAT Signaling, Interferon-gamma Pathway, TLR signaling, Response to Growth Hormone Stimulus
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