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SOCS1 抗体 (N-Term)

This 兔多克隆 antibody specifically detects SOCS1 in WB 和 IHC. It exhibits reactivity toward 人, 小鼠, 大鼠, Cow, Pig, 兔, 犬, 马和豚鼠.

SOCS1 antibody - N-terminal region validated by WB using Jurkat cell lysate at 0. (SOCS1 抗体 (N-Term))

Image no. 3 for anti-Suppressor of Cytokine Signaling 1 (SOCS1) (N-Term) antibody (ABIN2777164) (SOCS1 抗体 (N-Term))

WB Suggested Anti-SOCS1 Antibody Titration: 1. (SOCS1 抗体 (N-Term))

Host: Mouse Target Name: SOCS1 Sample Tissue: Mouse Pancreas Antibody Dilution: 1ug/ml (SOCS1 抗体 (N-Term))

Rabbit Anti-SOCS1 Antibody Paraffin Embedded Tissue: Human Kidney Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4. (SOCS1 抗体 (N-Term))

IHC

7 images

产品编号 ABIN2777164

发货至: 中国

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中国
北京 101111

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Quick Overview for SOCS1 抗体 (N-Term) (ABIN2777164)

抗原

See all SOCS1 抗体

SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))

适用

人, 小鼠, 大鼠, Cow, Pig, 兔, 犬, 马, 豚鼠

宿主

兔

克隆类型

多克隆

标记

This SOCS1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product SOCS1 Primary Antibody

抗原表位
11

11

8

8

2

2

2

1

1

1

1

1

1

1
N-Term

原理

SOCS1 Antibody - N-terminal region

序列

RRPEPSSSSS SSPAAPARPR PCPAVPAPAP GDTHFRTFRS HADYRRITRA

预测反应

Cow: 100%, Dog: 92%, Guinea Pig: 93%, Horse: 90%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against SOCS1. It was validated on Western Blot and immunohistochemistry.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human SOCS1
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 1-211) antibody
SOCS1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Suppressor of Cytokine Signaling 1 (SOCS1) (C-Term) antibody
Verified SOCS1 适用: 人, 小鼠 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 35-66), (N-Term) antibody
SOCS1 适用: 小鼠, 大鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB17347 unconjugated

anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 35-66) antibody
SOCS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-Suppressor of Cytokine Signaling 1 (SOCS1) (C-Term) antibody
SOCS1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 121-211) antibody
SOCS1 适用: 人 WB, IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Suppressor of Cytokine Signaling 1 (SOCS1) antibody
SOCS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Suppressor of Cytokine Signaling 1 (SOCS1) (C-Term) antibody
SOCS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Suppressor of Cytokine Signaling 1 (SOCS1) (N-Term) antibody
SOCS1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Suppressor of Cytokine Signaling 1 (SOCS1) (N-Term) antibody
SOCS1 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

说明

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42147-100UG

限制

仅限研究用
状态

Liquid

浓度

1.0 mg/mL

缓冲液

Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

prevent freeze-thaw cycles

储存条件

4 °C,-20 °C

储存方法

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
抗原

SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))

别名

SOCS1

背景

Background Information: SOCS1 is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. SOCS1 functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of its gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.
Gene Name: Suppressor of cytokine signaling 1
Alternative Symbols: JAB, CIS1, SSI1, TIP3, CISH1, SSI-1, TIP-3, SOCS-1
Protein Name: Suppressor of cytokine signaling 1

分子量

23kDa

基因ID

8651

NCBI登录号

NP_003736

UniProt

O15524

途径

JAK/STAT Signaling, Interferon-gamma Pathway, TLR signaling, Response to Growth Hormone Stimulus