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SSRP1 抗体

This anti-SSRP1 antibody is a 兔 多克隆 antibody detecting SSRP1 in WB, IHC, ELISA 和 IF. Suitable for 人 和 小鼠.
产品编号 ABIN7119562
发货至: 中国

Quick Overview for SSRP1 抗体 (ABIN7119562)

抗原

See all SSRP1 抗体
SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

适用

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人, 小鼠

宿主

  • 55
  • 4

克隆类型

  • 55
  • 4
多克隆

标记

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  • 1
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This SSRP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    structure specific recognition protein 1

    亚型

    IgG
  • 应用备注

    WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:10 - 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

    别名

    SSRP1

    背景

    Synonyms:FACT80 Background:The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.

    分子量

    Refer to figures

    基因ID

    6749

    UniProt

    Q08945

    途径

    Chromatin Binding
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