SPOP-B 抗体
Quick Overview for SPOP-B 抗体 (ABIN7119381)
抗原
See all SPOP-B 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- speckle-type POZ protein
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亚型
- IgG
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anti-Speckle-Type POZ Protein (SPOP-B) (Internal Region) antibody
SPOP-B 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 301-374) antibodySPOP-B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E2 unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 1-374) antibodySPOP-B 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (Center) antibodySPOP-B 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (C-Term) antibodySPOP-B 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 48-374) antibodySPOP-B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 74-107), (N-Term) antibodySPOP-B 适用: 小鼠, 斑马鱼 WB 宿主: 兔 Polyclonal RB49885 unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 1-374) antibodySPOP-B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (C-Term) antibodySPOP-B 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔, 小鸡, 非洲爪蟾, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 1-193) antibodySPOP-B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:50-1:500, IP : 1:500-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
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别名
- SPOP
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背景
- Synonyms:HIB homolog 1, Roadkill homolog 1, speckle type POZ protein, SPOP, TEF2 Background:Component of a cullin-RING-based BCR(BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3. In complex with CUL3, involved in ubiquitination of H2AFY and BMI1, this does not lead to their proteasomal degradation. Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation. The cullin-RING-based BCR(BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOP has higher ubiquitin ligase activity than the complex that contains the heterodimer formed by SPOP and SPOPL.
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分子量
- 42 kDa
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基因ID
- 8405
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UniProt
- O43791
抗原
-
