SOS1 抗体
Quick Overview for SOS1 抗体 (ABIN7119340)
抗原
See all SOS1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SOS1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- son of sevenless homolog 1
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IF: 1:50 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- SOS1 (Son of Sevenless Homolog 1 (SOS1))
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别名
- SOS1
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背景
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Synonyms: Son of sevenless homolog 1 (SOS-1)|SOS1
Background: Promotes the exchange of Ras-bound GDP by GTP(PubMed:8493579). Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF(PubMed:17339331). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor(GEF) activity(By similarity).
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分子量
- 180 kDa
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基因ID
- 6654
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UniProt
- Q07889
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途径
- RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
抗原
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