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SIRT1 抗体 (AA 1-350)

Name: SIRT1 抗体 (AA 1-350)
Brand: antibodies-online
SKU: ABIN7119109
Availability: OutOfStock

This anti-SIRT1 antibody is a 小鼠单克隆 antibody detecting SIRT1 in WB, IHC, ELISA 和 IP. Suitable for 人.

产品编号 ABIN7119109

发货至: 中国

Quick Overview for SIRT1 抗体 (AA 1-350) (ABIN7119109)

抗原

See all SIRT1 抗体

SIRT1 (Sirtuin 1 (SIRT1))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This SIRT1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

克隆位点

6A1

Discover our top product SIRT1 Primary Antibody

抗原表位
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2

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2

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1

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1

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1

1

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1

1

1
AA 1-350

原理

SIRT1 antibody

纯化方法

Protein A+G purification

纯度

≥95 % as determined by SDS-PAGE

免疫原

Immunogen sequence: 1-350aa
Immunogen: sirtuin(silent mating type information regulation 2 homolog) 1

亚型

IgG1
anti-Sirtuin 1 (SIRT1) (AA 101-200) antibody
SIRT1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 1 (SIRT1) (AA 448-747) antibody
SIRT1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 1 (SIRT1) (AA 456-555) antibody
SIRT1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 7B7 unconjugated

anti-Sirtuin 1 (SIRT1) (AA 566-601), (C-Term) antibody
SIRT1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB50965 unconjugated

anti-Sirtuin 1 (SIRT1) antibody
SIRT1 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1F3 unconjugated

anti-Sirtuin 1 (SIRT1) antibody
KO Validated SIRT1 适用: 人 WB, IHC, IP, IF, ChIP 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 1 (SIRT1) (N-Term) antibody
SIRT1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 1 (SIRT1) (AA 566-601) antibody
SIRT1 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Sirtuin 1 (SIRT1) (AA 456-555) antibody
SIRT1 适用: 人 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 7B7 unconjugated

anti-Sirtuin 1 (SIRT1) (pSer47) antibody
SIRT1 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:2000-1:5000, IP: 1:500-1:2000 for WB, IHC: 1:20-1:200

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze / thaw cycles.

储存条件

-20 °C

储存方法

-20°C for 12 months

有效期

12 months
抗原

SIRT1 (Sirtuin 1 (SIRT1))

别名

SIRT1

背景

Synonyms: NAD-dependent protein deacetylase sirtuin-1 (hSIRT1)|NAD-dependent protein deacylase sirtuin-1|Regulatory protein SIR2 homolog 1|SIR2-like protein 1 (hSIR2)|SirtT1 75 kDa fragment (75SirT1)|SIRT1|SIR2L1
Background: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.

分子量

130 kDa

基因ID

23411

UniProt

Q96EB6

途径

MAPK Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling