STAT2 抗体
Quick Overview for STAT2 抗体 (ABIN7119077)
抗原
See all STAT2 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- signal transducer and activator of transcription 2, 113kDa
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亚型
- IgG
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anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (AA 151-250) antibody
STAT2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (AA 616-849) antibodySTAT2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (AA 587-838) antibodySTAT2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (AA 742-851) antibodySTAT2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5G7 unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (C-Term) antibodySTAT2 适用: 人 WB, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (pTyr690) antibodySTAT2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), ICC, IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) antibodySTAT2 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal STAT2-2650 unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) antibodySTAT2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (AA 658-912) antibodySTAT2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (AA 571-851) antibodySTAT2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
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别名
- STAT2
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背景
- Synonyms: Background:Signal transducer and activator of transcription that mediates signaling by type I IFNs(IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases(TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element(ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state(PubMed:9020188, PubMed:23391734). Acts as a regulator of mitochondrial fission by modulating the phosphorylation of DNM1L at 'Ser-616' and 'Ser-637' which activate and inactivate the GTPase activity of DNM1L respectively(PubMed:26122121).
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分子量
- 113 kDa
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基因ID
- 6773
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UniProt
- P52630
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途径
- JAK/STAT Signaling, Hepatitis C, CXCR4-mediated Signaling Events
抗原
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