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Septin 2 抗体

This anti-Septin 2 antibody is a 兔 多克隆 antibody detecting Septin 2 in WB, ELISA, IHC, IF, IP 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7118879
发货至: 中国

Quick Overview for Septin 2 抗体 (ABIN7118879)

抗原

See all Septin 2 (SEPT2) 抗体
Septin 2 (SEPT2)

适用

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  • 35
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  • 4
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  • 4
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  • 2
  • 2
  • 1
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人, 小鼠, 大鼠

宿主

  • 72
  • 5
  • 1

克隆类型

  • 66
  • 13
多克隆

标记

  • 35
  • 5
  • 5
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  • 3
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  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This Septin 2 antibody is un-conjugated

应用范围

  • 37
  • 27
  • 14
  • 14
  • 9
  • 7
  • 6
  • 5
  • 4
  • 4
  • 3
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    septin 2

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:4000, IP: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    Septin 2 (SEPT2)

    别名

    SEPT2

    背景

    Synonyms:hNedd5, NEDD 5, NEDD5, SEPT2, SEPT2/septin 2, septin 2, septin2 Background:Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes: probably acts by regulating the assembly of the tectonic-like complex(also named B9 complex) by localizing TMEM231 protein. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.

    分子量

    45 kDa

    基因ID

    4735

    UniProt

    Q15019
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