RYK 抗体
Quick Overview for RYK 抗体 (ABIN7118742)
抗原
See all RYK 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- RYK antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- RYK receptor-like tyrosine kinase
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- RYK (RYK Receptor-Like Tyrosine Kinase (RYK))
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别名
- RYK
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背景
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Synonyms: Tyrosine-protein kinase RYK|RYK|JTK5A
Background: May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.
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分子量
- 68 kDa
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基因ID
- 6259
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UniProt
- P34925
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途径
- RTK signaling, WNT signaling, Regulation of Cell Size
抗原
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