ARHGEF18 抗体
Quick Overview for ARHGEF18 抗体 (ABIN7118503)
抗原
See all ARHGEF18 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ARHGEF18 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- rho/rac guanine nucleotide exchange factor(GEF) 18
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亚型
- IgG
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anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) (Center) antibody
ARHGEF18 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) (AA 159-551) antibodyARHGEF18 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) (C-Term) antibodyVerified ARHGEF18 适用: 人 ELISA, WB, IF 宿主: 山羊 Polyclonal unconjugated
anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) (AA 1-89) antibodyARHGEF18 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 8H6 unconjugated
anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) (AA 159-551) antibodyARHGEF18 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) antibody (HRP)ARHGEF18 适用: 人, 犬 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal HRP
anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) antibody (Biotin)ARHGEF18 适用: 人, 犬 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal Biotin
anti-rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18) antibody (FITC)ARHGEF18 适用: 人, 犬 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal FITC
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- ARHGEF18 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18))
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别名
- ARHGEF18
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背景
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Synonyms: Rho guanine nucleotide exchange factor 18|114 kDa Rho-specific guanine nucleotide exchange factor (p114-Rho-GEF, p114RhoGEF)|Septin-associated RhoGEF (SA-RhoGEF)|ARHGEF18|KIAA0521
Background: Acts as guanine nucleotide exchange factor(GEF) for RhoA GTPases. Its activation induces formation of actin stress fibers. Also act as a GEF for RAC1, inducing production of reactive oxygen species(ROS). Does not act as a GEF for CDC42. The G protein beta-gamma(Gbetagamma) subunits of heterotrimeric G proteins act as activators, explaining the integrated effects of LPA and other G-protein coupled receptor agonists on actin stress fiber formation, cell shape change and ROS production. Required for EPB41L4B-mediated regulation of the circumferential actomyosin belt in epithelial cells(PubMed:22006950).
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分子量
- 120-130 kDa
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基因ID
- 23370
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UniProt
- Q6ZSZ5
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途径
- Neurotrophin Signaling Pathway
抗原
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