FIP200 抗体
Quick Overview for FIP200 抗体 (ABIN7118327)
抗原
See all FIP200 (RB1CC1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- RB1CC1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 1480-1594
Immunogen: RB1-inducible coiled-coil 1
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亚型
- IgG
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anti-RB1-Inducible Coiled-Coil 1 (RB1CC1) (AA 501-600) antibody
RB1CC1 适用: 小鸡 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-RB1-Inducible Coiled-Coil 1 (RB1CC1) (C-Term) antibodyRB1CC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-RB1-Inducible Coiled-Coil 1 (RB1CC1) (AA 148-244) antibodyRB1CC1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2C9A11 unconjugated
anti-RB1-Inducible Coiled-Coil 1 (RB1CC1) (AA 1544-1594) antibodyRB1CC1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-RB1-Inducible Coiled-Coil 1 (RB1CC1) (C-Term) antibodyRB1CC1 适用: 人, 小鼠, 小鸡, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-RB1-Inducible Coiled-Coil 1 (RB1CC1) (C-Term) antibodyRB1CC1 适用: 人, 小鼠, 小鸡, 大鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-RB1-Inducible Coiled-Coil 1 (RB1CC1) (C-Term) antibodyRB1CC1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000-1:6000, IP:1:500-1:1000, IHC: 1:20-1:200, IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))
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别名
- RB1CC1
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背景
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Synonyms: RB1-inducible coiled-coil protein 1|FAK family kinase-interacting protein of 200 kDa (FIP200)|RB1CC1|KIAA0203|RBICC
Background: Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111. Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole(SCV) duting S.typhimurium infection and subsequent xenophagy. Autophagy positively regulates repair of DNA damage induced by ionizing radiation and negatively regulates apoptosis. Plays an indispensible role in fetal hematopoiesis and in the regulation of neuronal homeostasis(By similarity). Implicated in the regulation of RB1 expression. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. Expression is, thus, a prerequisite for myogenic differentiation. Inhibits PTK2/FAK1 and PTK2B/PYK2 activity and activation of downstream signaling pathways.
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分子量
- 200 kDa
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基因ID
- 9821
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UniProt
- Q8TDY2
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途径
- Regulation of Cell Size, Autophagy
抗原
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