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RAD23A 抗体

This anti-RAD23A antibody is a 兔 多克隆 antibody detecting RAD23A in WB, ELISA, IHC 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7118252
发货至: 中国

Quick Overview for RAD23A 抗体 (ABIN7118252)

抗原

See all RAD23A 抗体
RAD23A (RAD23 Homolog A (RAD23A))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This RAD23A antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    RAD23 homolog A(S. cerevisiae)

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    RAD23A (RAD23 Homolog A (RAD23A))

    别名

    RAD23A

    背景

    Synonyms: Background:Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucleotide excision repair(GG-NER) by association with XPC. In vitro, the XPC:RAD23A dimer has NER activity. Can stabilize XPC. Involved in vpr-dependent replication of HIV-1 in non-proliferating cells and primary macrophages. Required for the association of HIV-1 vpr with the host proteasome.

    分子量

    55 kDa

    基因ID

    5886

    UniProt

    P54725

    途径

    DNA Damage Repair
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