Src 抗体
Quick Overview for Src 抗体 (ABIN7118085)
抗原
See all Src 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SRC antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- v-src sarcoma(Schmidt-Ruppin A-2) viral oncogene homolog
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:500-1:2000, IHC: 1:100-1:400, IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
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别名
- SRC
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背景
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Synonyms: Proto-oncogene tyrosine-protein kinase Src|Proto-oncogene c-Src|pp60c-src (p60-Src)|SRC|SRC1
Background: SRC, also named as SRC1 and p60-Src, belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. It is a non-receptor protein tyrosine kinase that plays pivotal roles in numerous cellular processes such as proliferation, migration, and transformation. In concert with PTK2B, SRC plays an important role in osteoclastic bone resorption. It promotes energy production in osteoclasts by activating mitochondrial cytochrome C oxidase.
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分子量
- 55 kDa, 60 kDa
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基因ID
- 6714
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UniProt
- P12931
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途径
- JAK/STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
抗原
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