PPM1A 抗体
Quick Overview for PPM1A 抗体 (ABIN7118037)
抗原
See all PPM1A 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PPM1A antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- protein phosphatase 1A(formerly 2C), magnesium-dependent, alpha isoform
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))
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别名
- PPM1A
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背景
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Synonyms: Protein phosphatase 1A|Protein phosphatase 2C isoform alpha (PP2C-alpha)|Protein phosphatase IA|PPM1A|PPPM1A
Background: Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
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分子量
- 42 kDa
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基因ID
- 5494
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UniProt
- P35813
抗原
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