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PSMA7 抗体

This anti-PSMA7 antibody is a 兔 多克隆 antibody detecting PSMA7 in WB, IHC, ELISA, IP 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7117915
发货至: 中国

Quick Overview for PSMA7 抗体 (ABIN7117915)

抗原

See all PSMA7 抗体
PSMA7 (Proteasome Subunit alpha 7 (PSMA7))

适用

  • 55
  • 26
  • 17
  • 1
人, 小鼠, 大鼠

宿主

  • 46
  • 9

克隆类型

  • 47
  • 8
多克隆

标记

  • 27
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PSMA7 antibody is un-conjugated

应用范围

  • 46
  • 20
  • 15
  • 13
  • 8
  • 8
  • 7
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Flow Cytometry (FACS)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    proteasome(prosome, macropain) subunit, alpha type, 7

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    PSMA7 (Proteasome Subunit alpha 7 (PSMA7))

    别名

    PSMA7

    背景

    Synonyms:HSPC Background:The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH . The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor(AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.

    分子量

    28-30 kDa

    基因ID

    5688

    UniProt

    O14818

    途径

    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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