OSBP 抗体
Our Local Distributor
北京 101111
Quick Overview for OSBP 抗体 (ABIN7117171)
抗原
See all OSBP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- OSBP antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- oxysterol binding protein
-
亚型
- IgG
-
-
anti-Oxysterol Binding Protein (OSBP) (AA 508-807) antibody
OSBP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Oxysterol Binding Protein (OSBP) (Internal Region) antibodyOSBP 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Oxysterol Binding Protein (OSBP) (AA 324-407) antibodyOSBP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5A3 unconjugated
anti-Oxysterol Binding Protein (OSBP) (AA 700-749) antibodyOSBP 适用: 人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠, 马, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Oxysterol Binding Protein (OSBP) (AA 628-802) antibodyOSBP 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Oxysterol Binding Protein (OSBP) (C-Term) antibodyVerified OSBP 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Oxysterol Binding Protein (OSBP) (AA 546-807) antibodyOSBP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- OSBP (Oxysterol Binding Protein (OSBP))
-
别名
- OSBP
-
背景
-
Synonyms: Oxysterol-binding protein 1|OSBP|OSBP1
Background: Lipid transporter involved in lipid countertransport between the Golgi complex and membranes of the endoplasmic reticulum: specifically exchanges sterol with phosphatidylinositol 4-phosphate(PI4P), delivering sterol to the Golgi in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum(PubMed:24209621). Binds cholesterol and a range of oxysterols including 25-hydroxycholesterol(PubMed:15746430, PubMed:17428193). Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylates ERK1/2, whereas 25-hydroxycholesterol causes its disassembly(PubMed:15746430). Regulates cholesterol efflux by decreasing ABCA1 stability(PubMed:18450749).
-
分子量
- 89 kDa
-
基因ID
- 5007
-
UniProt
- P22059
抗原
-
