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OSBP 抗体 (AA 628-802)

OSBP 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7162395
发货至: 中国
  • 抗原 See all OSBP 抗体
    OSBP (Oxysterol Binding Protein (OSBP))
    抗原表位
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 628-802
    适用
    • 20
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 16
    • 3
    • 1
    克隆类型
    • 17
    • 3
    多克隆
    标记
    • 17
    • 1
    • 1
    • 1
    This OSBP antibody is un-conjugated
    应用范围
    • 16
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    ELISA, Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Oxysterol-binding protein 1 protein (628-802AA)
    亚型
    IgG
    Top Product
    Discover our top product OSBP Primary Antibody
  • 应用备注
    Recommended dilution: IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    OSBP (Oxysterol Binding Protein (OSBP))
    别名
    OSBP (OSBP 产品)
    别名
    CG6708 antibody, Dmel\\CG6708 antibody, OSBP-Dm antibody, osbp antibody, OSBP1 antibody, 1110018F06Rik antibody, AW559088 antibody, mKIAA4220 antibody, Oxysterol binding protein antibody, oxysterol binding protein antibody, Osbp antibody, OSBP antibody
    背景

    Background: Lipid transporter involved in lipid countertransport between the Golgi complex and membranes of the endoplasmic reticulum: specifically exchanges sterol with phosphatidylinositol 4-phosphate (PI4P), delivering sterol to the Golgi in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum (PubMed:24209621). Binds cholesterol and a range of oxysterols including 25-hydroxycholesterol (PubMed:15746430, PubMed:17428193). Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylates ERK1/2, whereas 25-hydroxycholesterol causes its disassembly (PubMed:15746430). Regulates cholesterol efflux by decreasing ABCA1 stability (PubMed:18450749).

    Aliases: OSBP 1 antibody, OSBP antibody, OSBP1_HUMAN antibody, Oxysterol binding protein 1 antibody, Oxysterol-binding protein 1 antibody

    UniProt
    P22059
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