OSBP 抗体 (Internal Region)
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- 抗原 See all OSBP 抗体
- OSBP (Oxysterol Binding Protein (OSBP))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This OSBP antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- OSBP Antibody detects endogenous levels of total OSBP.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human OSBP, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product OSBP Primary Antibody
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anti-Oxysterol Binding Protein (OSBP) (AA 324-407) antibody
OSBP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5A3 unconjugated
anti-Oxysterol Binding Protein (OSBP) (AA 508-807) antibodyOSBP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Oxysterol Binding Protein (OSBP) (AA 700-749) antibodyOSBP 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 猴, Pig, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Oxysterol Binding Protein (OSBP) (AA 628-802) antibodyOSBP 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Oxysterol Binding Protein (OSBP) (C-Term) antibodyVerified OSBP 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Oxysterol Binding Protein (OSBP) (AA 546-807) antibodyOSBP 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- OSBP (Oxysterol Binding Protein (OSBP))
- 别名
- OSBP (OSBP 产品)
- 别名
- CG6708 antibody, Dmel\\CG6708 antibody, OSBP-Dm antibody, osbp antibody, OSBP1 antibody, 1110018F06Rik antibody, AW559088 antibody, mKIAA4220 antibody, Oxysterol binding protein antibody, oxysterol binding protein antibody, Osbp antibody, OSBP antibody
- 背景
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Description: Lipid transporter involved in lipid countertransport between the Golgi complex and membranes of the endoplasmic reticulum: specifically exchanges sterol with phosphatidylinositol 4-phosphate (PI4P), delivering sterol to the Golgi in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum (PubMed:24209621). Binds cholesterol and a range of oxysterols including 25-hydroxycholesterol (PubMed:15746430, PubMed:17428193). Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylates ERK1/2, whereas 25-hydroxycholesterol causes its disassembly (PubMed:15746430). Regulates cholesterol efflux by decreasing ABCA1 stability (PubMed:18450749).
Gene: OSBP
- 分子量
- 89 kDa
- 基因ID
- 5007
- UniProt
- P22059
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