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NOTCH3 抗体

This anti-NOTCH3 antibody is a 兔 多克隆 antibody detecting NOTCH3 in WB, ELISA, IHC 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7116933
发货至: 中国

Quick Overview for NOTCH3 抗体 (ABIN7116933)

抗原

See all NOTCH3 抗体
NOTCH3 (Notch 3 (NOTCH3))

适用

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人, 小鼠, 大鼠

宿主

  • 42
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  • 3
  • 1
  • 1

克隆类型

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  • 18
多克隆

标记

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This NOTCH3 antibody is un-conjugated

应用范围

  • 26
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Notch homolog 3

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IP: 1:500-1:1000, IHC: 1:50-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    NOTCH3 (Notch 3 (NOTCH3))

    别名

    NOTCH3

    背景

    Synonyms:CADASIL, CASIL, Notch 3, Notch homolog 3, NOTCH3 Background:Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain(NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs(By similarity).

    分子量

    250-260 kDa, 100 kDa

    基因ID

    4854

    UniProt

    Q9UM47

    途径

    Notch Signaling
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