NOTCH3 抗体
Quick Overview for NOTCH3 抗体 (ABIN7116933)
抗原
See all NOTCH3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- NOTCH3 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- Notch homolog 3
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500-1:2000, IP: 1:500-1:1000, IHC: 1:50-1:500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- NOTCH3 (Notch 3 (NOTCH3))
-
别名
- NOTCH3
-
背景
-
Synonyms: Neurogenic locus notch homolog protein 3 (Notch 3)|Notch 3 extracellular truncation|Notch 3 intracellular domain|NOTCH3
Background: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain(NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs(By similarity).
-
分子量
- 250-260 kDa, 100 kDa
-
基因ID
- 4854
-
UniProt
- Q9UM47
-
途径
- Notch Signaling
抗原
-