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NOTCH3 抗体

The 兔 多克隆 anti-NOTCH3 antibody (ABIN7116933) specifically detects NOTCH3 in WB, ELISA, IHC 和 IP. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7116933
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for NOTCH3 抗体 (ABIN7116933)

抗原

See all NOTCH3 抗体
NOTCH3 (Notch 3 (NOTCH3))

适用

  • 57
  • 18
  • 10
  • 1
人, 小鼠, 大鼠

宿主

  • 41
  • 16
  • 3
  • 1
  • 1
  • 1
  • 1

克隆类型

  • 45
  • 20
多克隆

标记

  • 34
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This NOTCH3 antibody is un-conjugated

应用范围

  • 26
  • 24
  • 21
  • 8
  • 7
  • 4
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
  • 原理

    NOTCH3 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Notch homolog 3

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IP: 1:500-1:1000, IHC: 1:50-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    NOTCH3 (Notch 3 (NOTCH3))

    别名

    NOTCH3

    背景

    Synonyms: Neurogenic locus notch homolog protein 3 (Notch 3)|Notch 3 extracellular truncation|Notch 3 intracellular domain|NOTCH3

    Background: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain(NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs(By similarity).

    分子量

    250-260 kDa, 100 kDa

    基因ID

    4854

    UniProt

    Q9UM47

    途径

    Notch Signaling
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