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NOTCH3 抗体 (AA 47-156)

NOTCH3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G5 unconjugated
产品编号 ABIN562028
发货至: 中国
  • 抗原 See all NOTCH3 抗体
    NOTCH3 (Notch 3 (NOTCH3))
    抗原表位
    • 14
    • 11
    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 47-156
    适用
    • 50
    • 16
    • 11
    • 1
    宿主
    • 34
    • 16
    • 2
    • 1
    • 1
    小鼠
    克隆类型
    • 38
    • 17
    单克隆
    标记
    • 30
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NOTCH3 antibody is un-conjugated
    应用范围
    • 27
    • 25
    • 22
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    原理
    Mouse monoclonal antibody raised against a partial recombinant NOTCH3.
    序列
    SPCANGGRCT QLPSREAACL CPPGWVGERC QLEDPCHSGP CAGRGVCQSS VVAGTARFSC RCPRGFRGPD CSLPDPCLSS PCAHGARCSV GPDGRFLCSC PPGYQGRSCR
    交叉反应
    产品特性
    Antibody Reactive Against Recombinant Protein.
    免疫原
    NOTCH3 (NP_000426, 47 a.a. ~ 156 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    克隆位点
    1G5
    亚型
    IgG2a
    Top Product
    Discover our top product NOTCH3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    In 1x PBS, pH 7.4
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Meng, Zhang, Lee, Wang: "Von Willebrand factor inhibits mature smooth muscle gene expression through impairment of Notch signaling." in: PLoS ONE, Vol. 8, Issue 9, pp. e75808, (2013) (PubMed).

    Watanabe-Hosomi, Watanabe, Tanaka, Nakagawa, Mizuno: "Transendocytosis is impaired in CADASIL-mutant NOTCH3." in: Experimental neurology, Vol. 233, Issue 1, pp. 303-11, (2012) (PubMed).

    Tada, Itoh, Ishii-Watabe, Suzuki, Kawasaki: "Functional analysis of the Notch ligand Jagged1 missense mutant proteins underlying Alagille syndrome." in: The FEBS journal, Vol. 279, Issue 12, pp. 2096-107, (2012) (PubMed).

    Dong, Blaivas, Wang: "Bidirectional encroachment of collagen into the tunica media in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy." in: Brain research, Vol. 1456, pp. 64-71, (2012) (PubMed).

    Lee, Meng, Elmadhoun, Blaivas, Wang: "Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy affecting an African American man: identification of a novel 15-base pair NOTCH3 duplication." in: Archives of neurology, Vol. 68, Issue 12, pp. 1584-6, (2011) (PubMed).

    Meng, Zhang, Hankenson, Wang: "Thrombospondin 2 potentiates notch3/jagged1 signaling." in: The Journal of biological chemistry, Vol. 284, Issue 12, pp. 7866-74, (2009) (PubMed).

    Park, Shih, Wang: "Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer." in: Cancer research, Vol. 68, Issue 21, pp. 8852-60, (2008) (PubMed).

  • 抗原
    NOTCH3 (Notch 3 (NOTCH3))
    别名
    NOTCH3 (NOTCH3 产品)
    别名
    CADASIL antibody, CASIL antibody, IMF2 antibody, AW229011 antibody, N3 antibody, hpbk antibody, fa14b08 antibody, notch5 antibody, wu:fa14b08 antibody, notch 3 antibody, NOTCH3 antibody, Notch3 antibody, notch3 antibody
    背景
    Full Gene Name: Notch homolog 3 (Drosophila)
    Synonyms: CADASIL,CASIL
    基因ID
    4854
    NCBI登录号
    NM_000435
    途径
    Notch Signaling
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