NLRX1 抗体
Quick Overview for NLRX1 抗体 (ABIN7116905)
抗原
See all NLRX1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- NLRX1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- NLR family member X1
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:500-1:1000, IHC: 1:50-1:500, IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- NLRX1 (NLR Family Member X1 (NLRX1))
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别名
- NLRX1
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背景
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Synonyms: NLR family member X1|Caterpiller protein 11.3 (CLR11.3)|Nucleotide-binding oligomerization domain protein 5|Nucleotide-binding oligomerization domain protein 9|NLRX1|NOD5|NOD9
Background: Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH(RIG-like helicase)-MAVS interaction(PubMed:18200010). Has no inhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species(PubMed:18219313).
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分子量
- 110 kDa
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基因ID
- 79671
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UniProt
- Q86UT6
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途径
- SARS-CoV-2 Protein Interactome
抗原
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