MAML1 抗体
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北京 101111
Quick Overview for MAML1 抗体 (ABIN7116076)
抗原
See all MAML1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- MAML1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- mastermind-like 1(Drosophila)
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亚型
- IgG
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anti-Mastermind-Like 1 (MAML1) (N-Term) antibody
MAML1 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mastermind-Like 1 (MAML1) (AA 1-45) antibodyMAML1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mastermind-Like 1 (MAML1) (N-Term) antibodyVerified MAML1 适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Mastermind-Like 1 (MAML1) (AA 655-754) antibodyMAML1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mastermind-Like 1 (MAML1) (AA 198-225) antibodyMAML1 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB18757 unconjugated
anti-Mastermind-Like 1 (MAML1) (AA 205-234), (Middle Region) antibodyMAML1 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- MAML1 (Mastermind-Like 1 (MAML1))
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别名
- MAML1
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背景
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Synonyms: Mastermind-like protein 1 (Mam-1)|MAML1|KIAA0200
Background: Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions.
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分子量
- 108-120 kDa
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基因ID
- 9794
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UniProt
- Q92585
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途径
- Notch Signaling, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
-
