IL-18 抗体
Quick Overview for IL-18 抗体 (ABIN7115433)
抗原
See all IL-18 (IL18) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Pre-IL18 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- interleukin 18(interferon-gamma-inducing factor)
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:500-1:5000 , IHC: 1:50-1:500, IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- IL-18 (IL18) (Interleukin 18 (IL18))
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别名
- Pre-IL18
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背景
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Synonyms: Interleukin-18 (IL-18)|Iboctadekin|Interferon gamma-inducing factor (IFN-gamma-inducing factor)|Interleukin-1 gamma (IL-1 gamma)|IL18|IGIF|IL1F4
Background: IL18, is a proinflammatory cytokine involved in the development of Th1 cells and in immune response. It can stimulate the NK cells and certain T cells to release interferon gamma which plays an important role in activating the macrophages or other cells. IL18 has been demonstrated to have the potential to enhance Fas ligand-mediated cytotoxicity, which is increased in PE and regulates placental apoptosis. IL18 is synthesized as a 24 kDa precursor and then cleaved into a biologically activate 18 kDa form. This antibody is raised against the full length IL18 precursor, and it recognizes both the pre-IL18 and mature IL18 theoretically.
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分子量
- 24 kDa
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UniProt
- Q14116
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途径
- Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
抗原
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