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ITGA5 抗体

This anti-ITGA5 antibody is a 兔 多克隆 antibody detecting ITGA5 in WB 和 ELISA. Suitable for 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN7115337
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ITGA5 抗体 (ABIN7115337)

抗原

See all ITGA5 抗体
ITGA5 (Integrin, alpha 5 (ITGA5))

适用

  • 121
  • 79
  • 33
  • 2
  • 2
  • 2
人, 小鼠, 大鼠, 猴

宿主

  • 99
  • 19
  • 10
  • 7
  • 4

克隆类型

  • 77
  • 63
多克隆

标记

  • 68
  • 12
  • 11
  • 9
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ITGA5 antibody is un-conjugated

应用范围

  • 86
  • 52
  • 44
  • 44
  • 25
  • 20
  • 17
  • 15
  • 14
  • 13
  • 10
  • 3
  • 1
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  • 1
Western Blotting (WB), ELISA
  • 原理

    ITGA5 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    integrin, alpha 5

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    ITGA5 (Integrin, alpha 5 (ITGA5))

    别名

    ITGA5

    背景

    Synonyms: Integrin alpha-5|CD49 antigen-like family member E|Fibronectin receptor subunit alpha|Integrin alpha-F|VLA-5|Integrin alpha-5 heavy chain|Integrin alpha-5 light chain|ITGA5|FNRA

    Background: Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site(site 2) which is distinct from the classical ligand-binding site(site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1(PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 acts as a receptor for fibrillin-1(FBN1) and mediates R-G-D-dependent cell adhesion to FBN1(PubMed:12807887, PubMed:17158881).

    分子量

    120 kDa

    UniProt

    P08648

    途径

    Integrin Complex
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