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VEGFA 抗体 (AA 141-180)

This anti-VEGFA antibody is a 兔 多克隆 antibody detecting VEGFA in WB, ELISA, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人, 大鼠, 小鼠 和 小鸡. This Primary Antibody has been cited in 6+ publications.
产品编号 ABIN707186
发货至: 中国

Quick Overview for VEGFA 抗体 (AA 141-180) (ABIN707186)

抗原

See all VEGFA 抗体
VEGFA (Vascular Endothelial Growth Factor A (VEGFA))

适用

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人, 大鼠, 小鼠, 小鸡

宿主

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克隆类型

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多克隆

标记

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This VEGFA antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 141-180

    交叉反应

    小鸡, 人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Sheep,Pig,Guinea Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human VEGF-A

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Fetoni, Eramo, Paciello, Rolesi, Samengo, Paludetti, Troiani, Pani: "The redox protein p66(shc) mediates cochlear vascular dysfunction and transient noise-induced hearing loss." in: Scientific reports, Vol. 6, pp. 25450, (2016) (PubMed).

    Shi, Ko, Ko, Kim, Ko: "Peptide Lv augments L-type voltage-gated calcium channels through vascular endothelial growth factor receptor 2 (VEGFR2) signaling." in: Biochimica et biophysica acta, Vol. 1853, Issue 5, pp. 1154-64, (2015) (PubMed).

    Wang, Liao, Wang, Deng, Yu: "Transplantation of bone marrow stromal cells overexpressing human vascular endothelial growth factor 165 enhances tissue repair in a rat model of radiation-induced injury." in: Chinese medical journal, Vol. 127, Issue 6, pp. 1093-9, (2014) (PubMed).

    Fetoni, Lattanzi, Eramo, Barba, Paciello, Moriconi, Rolesi, Michetti, Troiani, Paludetti: "Grafting and early expression of growth factors from adipose-derived stem cells transplanted into the cochlea, in a Guinea pig model of acoustic trauma." in: Frontiers in cellular neuroscience, Vol. 8, pp. 334, (2014) (PubMed).

    Tian, Yang, Xiao, Huang, He, Ma, Xia, Shi: "Mechanisms of neuroprotection from hypoxia-ischemia (HI) brain injury by up-regulation of cytoglobin (CYGB) in a neonatal rat model." in: The Journal of biological chemistry, Vol. 288, Issue 22, pp. 15988-6003, (2013) (PubMed).

  • 抗原

    VEGFA (Vascular Endothelial Growth Factor A (VEGFA))

    别名

    VEGF-A

    背景

    Synonyms: VPF, VEGF, MVCD1, Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VEGFA

    Background: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.

    基因ID

    7422

    UniProt

    P15692

    途径

    RTK signaling, Glycosaminoglycan Metabolic Process, Regulation of Cell Size, Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
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