EYA1 抗体
Quick Overview for EYA1 抗体 (ABIN7114028)
抗原
See all EYA1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- EYA1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- eyes absent homolog 1(Drosophila)
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亚型
- IgG
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anti-Eyes Absent Homolog 1 (EYA1) (AA 100-170) antibody
EYA1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Eyes Absent Homolog 1 (EYA1) (AA 100-250) antibodyEYA1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eyes Absent Homolog 1 (EYA1) (Middle Region) antibodyEYA1 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 兔, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eyes Absent Homolog 1 (EYA1) (AA 168-321) antibodyEYA1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Eyes Absent Homolog 1 (EYA1) (Internal Region) antibodyVerified EYA1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Eyes Absent Homolog 1 (EYA1) (C-Term) antibodyEYA1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- EYA1 (Eyes Absent Homolog 1 (EYA1))
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别名
- EYA1
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背景
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Synonyms: Eyes absent homolog 1|EYA1
Background: Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5(By similarity). Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX(H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress(PubMed:19234442). Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis(By similarity). Has also phosphatase activity with proteins phosphorylated on Ser and Thr residues(in vitro)(By similarity). Required for normal embryonic development of the craniofacial and trunk skeleton, kidneys and ears(By similarity). Together with SIX1, it plays an important role in hypaxial muscle development, in this it is functionally redundant with EYA2(By similarity).
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分子量
- 60 kDa,50 kDa
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基因ID
- 2138
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UniProt
- Q99502
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途径
- Sensory Perception of Sound, Positive Regulation of Response to DNA Damage Stimulus
抗原
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