Exportin 7 抗体
Quick Overview for Exportin 7 抗体 (ABIN7114023)
抗原
See all Exportin 7 (XPO7) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- exportin 7
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亚型
- IgG
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anti-Exportin 7 (XPO7) antibody
XPO7 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Exportin 7 (XPO7) (C-Term) antibodyVerified XPO7 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Exportin 7 (XPO7) (C-Term) antibodyXPO7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Exportin 7 (XPO7) (C-Term) antibodyXPO7 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 斑马鱼, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:5000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- Exportin 7 (XPO7)
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别名
- XPO7
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背景
- Synonyms:Exp7, exportin 7, KIAA0745, Ran binding protein 16, RANBP16, XPO7 Background:Mediates the nuclear export of proteins(cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex(NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP(induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO7 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus.
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分子量
- 100 kDa
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基因ID
- 23039
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UniProt
- Q9UIA9
抗原
-
