Exportin 7 抗体
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北京 101111
Quick Overview for Exportin 7 抗体 (ABIN7232184)
抗原
See all Exportin 7 (XPO7) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-XPO7 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of XPO7 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human XPO7 protein
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亚型
- IgG
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anti-Exportin 7 (XPO7) antibody
XPO7 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Exportin 7 (XPO7) (C-Term) antibodyXPO7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Exportin 7 (XPO7) (C-Term) antibodyVerified XPO7 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Exportin 7 (XPO7) (AA 1-50) antibodyXPO7 适用: 人, 小鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Exportin 7 (XPO7) (C-Term) antibodyXPO7 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 斑马鱼, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- Exportin 7 (XPO7)
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别名
- XPO7
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背景
- Exportin-7, Exp7, Ran-binding protein 16Mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO7 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
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分子量
- 119kD
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基因ID
- 23039
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UniProt
- Q9UIA9
抗原
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