Diazepam Binding Inhibitor 抗体
Quick Overview for Diazepam Binding Inhibitor 抗体 (ABIN7113469)
抗原
See all Diazepam Binding Inhibitor (DBI) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein)
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
-
有效期
- 12 months
-
-
- Diazepam Binding Inhibitor (DBI)
-
别名
- DBI
-
背景
- Synonyms:DBI, ACBD1, ACBP, CCK-RP, EP, acyl-CoA-binding protein Background:This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.
-
分子量
- 12 kDa
-
基因ID
- 1622
-
UniProt
- P07108
抗原
-