DLL4 抗体
Quick Overview for DLL4 抗体 (ABIN7113410)
抗原
See all DLL4 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- DLL4 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- delta-like 4(Drosophila)
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- DLL4 (delta-Like 4 (DLL4))
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别名
- DLL4
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背景
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Synonyms: Delta-like protein 4|Drosophila Delta homolog 4 (Delta4)|DLL4
Background: Involved in the Notch signaling pathway as Notch ligand(PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting(PubMed:20616313). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types(By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate(PubMed:17728344).
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分子量
- 75-80 kDa
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基因ID
- 54567
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UniProt
- Q9NR61
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途径
- Notch Signaling
抗原
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