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COPS7A 抗体

This anti-COPS7A antibody is a 兔 多克隆 antibody detecting COPS7A in WB, ELISA, IHC 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7113043
发货至: 中国

Quick Overview for COPS7A 抗体 (ABIN7113043)

抗原

See all COPS7A 抗体
COPS7A (COP9 Signalosome Complex Subunit 7a (COPS7A))

适用

  • 45
  • 26
  • 19
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
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  • 1
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人, 小鼠, 大鼠

宿主

  • 44
  • 1

克隆类型

  • 45
多克隆

标记

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  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This COPS7A antibody is un-conjugated

应用范围

  • 34
  • 16
  • 13
  • 5
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
  • 原理

    COPS7A antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    COP9 constitutive photomorphogenic homolog subunit 7A(Arabidopsis)

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    COPS7A (COP9 Signalosome Complex Subunit 7a (COPS7A))

    别名

    COPS7A

    背景

    Synonyms: COP9 signalosome complex subunit 7a (SGN7a, Signalosome subunit 7a)|Dermal papilla-derived protein 10|JAB1-containing signalosome subunit 7a|COPS7A|CSN7A|DERP10

    Background: Component of the COP9 signalosome complex(CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin(Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

    分子量

    30 kDa

    基因ID

    50813

    UniProt

    Q9UBW8

    途径

    Cell Division Cycle
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