COBRA1 抗体
Quick Overview for COBRA1 抗体 (ABIN7112923)
抗原
See all COBRA1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- NELFB antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- cofactor of BRCA1
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:500-1:1000, IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- COBRA1 (Cofactor of BRCA1 (COBRA1))
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别名
- NELFB
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背景
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Synonyms: Negative elongation factor B (NELF-B)|Cofactor of BRCA1|NELFB|COBRA1|KIAA1182
Background: Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. May be able to induce chromatin unfolding.
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分子量
- 66 kDa
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基因ID
- 25920
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UniProt
- Q8WX92
抗原
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