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CHMP4B 抗体

This anti-CHMP4B antibody is a 兔 多克隆 antibody detecting CHMP4B in IHC, ELISA 和 WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7112648
发货至: 中国

Quick Overview for CHMP4B 抗体 (ABIN7112648)

抗原

See all CHMP4B 抗体
CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))

适用

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  • 21
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  • 1
人, 小鼠, 大鼠

宿主

  • 38
  • 1

克隆类型

  • 38
  • 1
多克隆

标记

  • 13
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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  • 1
This CHMP4B antibody is un-conjugated

应用范围

  • 14
  • 13
  • 13
  • 13
  • 12
  • 8
  • 5
  • 3
  • 3
  • 3
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    chromatin modifying protein 4B

    亚型

    IgG
  • 应用备注

    WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))

    别名

    CHMP4B

    背景

    Synonyms:C20orf178, SHAX1 Background:This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts.

    分子量

    35 kDa

    基因ID

    128866

    UniProt

    Q9H444
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