电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

CHMP4B 抗体 (N-Term)

CHMP4B 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24088 unconjugated
产品编号 ABIN653481
发货至: 中国
  • 抗原 See all CHMP4B 抗体
    CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))
    抗原表位
    • 15
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    AA 51-79, N-Term
    适用
    • 44
    • 22
    • 14
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 43
    • 1
    克隆类型
    • 43
    • 1
    多克隆
    标记
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHMP4B antibody is un-conjugated
    应用范围
    • 19
    • 19
    • 18
    • 13
    • 13
    • 11
    • 4
    • 3
    • 3
    • 3
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    C, Zf, M, X
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This CHMP4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human CHMP4B.
    克隆位点
    RB24088
    亚型
    Ig Fraction
    Top Product
    Discover our top product CHMP4B Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Hu, Jiang, Chen, Wei, Zhang, Zhao, Ni, Lu, Wan: "High CHMP4B expression is associated with accelerated cell proliferation and resistance to doxorubicin in hepatocellular carcinoma." in: Tumour biology, Vol. 36, Issue 4, pp. 2569-81, (2015) (PubMed).

  • 抗原
    CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))
    别名
    CHMP4B (CHMP4B 产品)
    别名
    C20orf178 antibody, CHMP4A antibody, CTPP3 antibody, CTRCT31 antibody, SNF7 antibody, SNF7-2 antibody, Shax1 antibody, VPS32B antibody, Vps32-2 antibody, dJ553F4.4 antibody, 2010012F05Rik antibody, C76846 antibody, Snf7-2 antibody, RGD1309846 antibody, RGD1565889 antibody, CHMP4b antibody, chmp4b antibody, chmp4b.S antibody, CHMP4c antibody, c20orf178 antibody, wu:fc96b02 antibody, zgc:55566 antibody, charged multivesicular body protein 4B antibody, charged multivesicular body protein 4Ba antibody, charged multivesicular body protein 4B L homeolog antibody, charged multivesicular body protein 4Bb antibody, CHMP4B antibody, Chmp4b antibody, chmp4ba antibody, chmp4b.L antibody, chmp4bb antibody
    背景
    CHMP4B is a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies.
    分子量
    24950
    基因ID
    128866
    NCBI登录号
    NP_789782
    UniProt
    Q9H444
You are here:
客服