ATG4B 抗体
Quick Overview for ATG4B 抗体 (ABIN7111893)
抗原
See all ATG4B 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- ATG4B antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- ATG4 autophagy related 4 homolog B
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500-1:2000, IP: 1:500-1:2000 , IHC: 1:20-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))
-
别名
- ATG4B
-
背景
-
Synonyms: Cysteine protease ATG4B|AUT-like 1 cysteine endopeptidase|Autophagy-related cysteine endopeptidase 1 (Autophagin-1)|Autophagy-related protein 4 homolog B (HsAPG4B, hAPG4B)|ATG4B|APG4B|AUTL1|KIAA0943
Background: Cysteine protease required for the cytoplasm to vacuole transport(Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine(PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
-
分子量
- 44 kDa
-
基因ID
- 23192
-
UniProt
- Q9Y4P1
-
途径
- Autophagy
抗原
-