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alpha 2 Macroglobulin 抗体 (AA 1100-1474)

This anti-alpha 2 Macroglobulin antibody is a 小鼠 单克隆 antibody detecting alpha 2 Macroglobulin in WB, IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7111503
发货至: 中国

Quick Overview for alpha 2 Macroglobulin 抗体 (AA 1100-1474) (ABIN7111503)

抗原

See all alpha 2 Macroglobulin (A2M) 抗体
alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This alpha 2 Macroglobulin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA

克隆位点

6D0
  • 抗原表位

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    AA 1100-1474

    原理

    A2M antibody

    纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 1100-1474aa

    Immunogen: alpha-2-macroglobulin

    亚型

    IgG2a
  • 应用备注

    WB: 1:500-1:2000, IP: 1:500-1:1000, IF: 1:50-1:500, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

    别名

    A2M

    背景

    Synonyms: Alpha-2-macroglobulin (Alpha-2-M)|C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5|A2M|CPAMD5

    Background: Alpha-2-macroglobulin, also known as α2-macroglobulin(α2M or A2M), is a protein abundant in the plasma of vertebrates and several invertebrates. A2M is an evolutionarily conserved arm of the innate immune system. It also mediates the proliferation of T cells and macrophages. A2M acts as a nonspecific protease inhibitor involved in the host defense mechanism that inactivates both endogenous and exogenous proteases, including trypsin, thrombin and collagenase. Even though A2M is produced predominantly by the liver, it may also be expressed in the reproductive tract, heart, and brain, and may have important roles in many physiological processes and medical illnesses including Alzheimer's disease.

    分子量

    185 kDa

    基因ID

    2

    UniProt

    P01023

    途径

    Lipid Metabolism
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