alpha 2 Macroglobulin 抗体 (AA 1100-1474)
Quick Overview for alpha 2 Macroglobulin 抗体 (AA 1100-1474) (ABIN7111503)
抗原
See all alpha 2 Macroglobulin (A2M) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1100-1474
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原理
- A2M antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 1100-1474aa
Immunogen: alpha-2-macroglobulin
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亚型
- IgG2a
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应用备注
- WB: 1:500-1:2000, IP: 1:500-1:1000, IF: 1:50-1:500, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))
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别名
- A2M
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背景
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Synonyms: Alpha-2-macroglobulin (Alpha-2-M)|C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5|A2M|CPAMD5
Background: Alpha-2-macroglobulin, also known as α2-macroglobulin(α2M or A2M), is a protein abundant in the plasma of vertebrates and several invertebrates. A2M is an evolutionarily conserved arm of the innate immune system. It also mediates the proliferation of T cells and macrophages. A2M acts as a nonspecific protease inhibitor involved in the host defense mechanism that inactivates both endogenous and exogenous proteases, including trypsin, thrombin and collagenase. Even though A2M is produced predominantly by the liver, it may also be expressed in the reproductive tract, heart, and brain, and may have important roles in many physiological processes and medical illnesses including Alzheimer's disease.
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分子量
- 185 kDa
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基因ID
- 2
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UniProt
- P01023
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途径
- Lipid Metabolism
抗原
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