alpha Adaptin 抗体
Quick Overview for alpha Adaptin 抗体 (ABIN7111307)
抗原
See all alpha Adaptin (AP2A1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- AP2A1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- adaptor-related protein complex 2, alpha 1 subunit
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))
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别名
- AP2A1
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背景
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Synonyms: AP-2 complex subunit alpha-1|100 kDa coated vesicle protein A|Adaptor protein complex AP-2 subunit alpha-1|Adaptor-related protein complex 2 subunit alpha-1|Alpha-adaptin A|Alpha1-adaptin|Clathrin assembly protein complex 2 alpha-A large chain|Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit|AP2A1|ADTAA|CLAPA1
Background: This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined.
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分子量
- 108 kDa
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基因ID
- 160
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UniProt
- O95782
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途径
- Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation
抗原
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