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alpha Actinin 4 抗体

This anti-alpha Actinin 4 antibody is a 兔 多克隆 antibody detecting alpha Actinin 4 in WB, ELISA, IHC, IP, IF 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7111233
发货至: 中国

Quick Overview for alpha Actinin 4 抗体 (ABIN7111233)

抗原

See all alpha Actinin 4 (ACTN4) 抗体
alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

适用

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人, 小鼠, 大鼠

宿主

  • 93
  • 18

克隆类型

  • 78
  • 32
多克隆

标记

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This alpha Actinin 4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    actinin, alpha 4

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:5000, IHC: 1:20-1:200, IP: 1:500-1:5000, IF: 1:10-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

    别名

    ACTN4

    背景

    Synonyms:ACTININ 4, actinin, alpha 4, ACTN4, Alpha actinin 4, DKFZp686K23158, F actin cross linking protein, FSGS, FSGS1, Non muscle alpha actinin 4 Background:F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein(Probable). Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation(PubMed:15772161). Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions(By similarity). May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA(PubMed:22351778).

    分子量

    105 kDa

    基因ID

    81

    UniProt

    O43707

    途径

    Proton Transport
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