alpha Actinin 4 抗体 (AA 720-911)
Quick Overview for alpha Actinin 4 抗体 (AA 720-911) (ABIN7111233)
抗原
See all alpha Actinin 4 (ACTN4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 720-911
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原理
- ACTN4 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 720-911aa
Immunogen: actinin, alpha 4
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亚型
- IgG
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应用备注
- WB: 1:500-1:5000, IHC: 1:20-1:200, IP: 1:500-1:5000, IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
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别名
- ACTN4
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背景
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Synonyms: Alpha-actinin-4|Non-muscle alpha-actinin 4|ACTN4
Background: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein(Probable). Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation(PubMed:15772161). Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions(By similarity). May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA(PubMed:22351778).
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分子量
- 105 kDa
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基因ID
- 81
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UniProt
- O43707
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途径
- Proton Transport
抗原
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