IL-6 Receptor 抗体 (AA 20-365)
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Quick Overview for IL-6 Receptor 抗体 (AA 20-365) (ABIN7092952)
抗原
See all IL-6 Receptor (IL6R) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 20-365
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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免疫原
- Recombinant human IL6R(Leu20-Pro365) (ABIN6964085) produced by using human HEK293 cells
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亚型
- IgG
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应用备注
- ELISA 1/5000-10000,Flow Cyt 1/100
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute with deionized water
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
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别名
- IL6R
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背景
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Synonyms:CD126, gp80, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ
Description:This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9. -
分子量
- 51.5KDa
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途径
- JAK/STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
抗原
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