EGFR 抗体 (AA 25-645)
Quick Overview for EGFR 抗体 (AA 25-645) (ABIN7092929)
抗原
See all EGFR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 25-645
-
纯化方法
- Purified from cell culture supernatant by affinity chromatography
-
免疫原
- Recombinant human EGFR(Leu25-Ser645) (ABIN6964078) produced by using human HEK293 cells
-
亚型
- IgG
-
-
-
-
应用备注
- ELISA 1/5000-10000,Flow Cyt 1/100
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Reconstitute with deionized water
-
缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
-
有效期
- 12 months
-
-
- EGFR (Epidermal Growth Factor Receptor (EGFR))
-
别名
- EGFR
-
背景
-
Synonyms:EGFR,ERBB,ERBB1,HER1,PIG61,mENA
Description:The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. -
分子量
- 69.4 kDa
-
基因ID
- 1956
-
UniProt
- P00533
-
途径
- NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
抗原
-